Phosphorus compounds that give positive agent

Figure 4. Phosphorus compounds that give positive Mo ion tests without a reducing agent.

Shifting the side chain to the 4 position (with the necessary tautomeric change) affords an agent with local anesthetic and coronary vasodilator activity. Cycllzation of compound 147 by means of phosphorus oxychloride gives the amino-l,2,4-oxodiazole (148). Alkylation of that compound with 2-chlorotriethylamine in the presence of sodium hydroxide proceeds via the tautomer,... 

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