Phosphoramidites and Related Compounds

2 Phosphoramidites and Related Compounds. - Stepwise reactions between rescorcinol and tris(dialkylamino)phosphines have been used to build up intermediates which have undergone ultimate cyclisation to form macrocyclic aminophosphites, e.g. (155), of interest as analogues of crown ether ligands.  

Goerlich, A. Fischer and R. Schmutzler, Z. Anorg. Allg. Chem., 

Manger, U. Schmidt, G. Fries, D. Barth, B. Webemdorfer, D. A. Vicic, W. D. Jones and H. Werner, J. Chem. Soc., Dalton Trans., 1999,1867. 

Le Gendre, M. Offenbecher, C. Bruneau and P. H. Dixneuf, Tetrahedron-Asymmetry, 1998,9,2279. 

Brunett, R. Chauvin, J. Chiffre, B. Donnadieu, S. Huguet, P. Leglaye and E. Mothes, Inorg. Chim. Acta., 1999, 291, 300. 

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Phosphorochloridites (Chloroalkoxyphosphines) and Related Compounds 2.8.32 Phosphoramidites (Dialkylaminodialkoxyphosphines)... 

Acid salts of imidazole- and benzimidazole-related compounds have been evaluated as alternative promoters to the various activators developed for the condensation of a nucleoside phosphoramidite and a nucleoside. The acid/azole complexes were developed to circumvent some of the disadvantages most commonly encountered in both solution- and solid-phases. Azolium promoters were shown to achieve high yielding coupling reactions even with nucleosides of low reactivity. Hayakawa has also reviewed and broadened the recent phosphoramidite methodologies by describing the versatility of allyl and allyloxycar-... 

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