Phospholipid vesicles differential scanning calorimetry

Differential scanning calorimetry was performed to measure the chain melting temperature for non-cross-linked phospholipids (NCP) 1-3. Non-cross-linked vesicle dispersions (NCVD) and cross-linked vesicle dispersions (CVD) of 1 and 2 were also measured along with the chain melting transition of CVD-1 with a hydrophobic dye entrapped. Parent phospholipids DPPE and DLPE were used as references for NCP 1 and 2. Parent phospholipid EGGPE was used as reference for phospholipid 3. NCPs were weighed directly into the DSC pans. Vesicle dispersions were used for the non-cross-linked vesicle samples and freeze-dried powder was used for the cross-linked vesicle dispersion samples. 

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