Phosphoenolpyruvate carboxytransphosphorylase activities

Cooper TG, Tchen TT, Wood HG, Benedict CR. (1968). The carboxylation of phospho-enolpyruvate and pyruvate. I. The active species of COj utilized by phosphoenolpyruvate carboxykinase, carboxytransphosphorylase, and pyruvate carboxylase. J Biol Chem, 243, 3857-3863. 

The reaction of CO2 fixation onto phosphoenolpyruvic acid by PEP carboxytransphosphorylase is considered (O Brien and Wood, 1974) as a control mechanism of propionic acid fermentation. They observed a conversion of the enzymatically active tetrameric form of PEP carboxytransphosphorylase isolated from P. shermanii into a less active dimeric form induced by oxalate, malate and fumarate. Therefore, the loss of activity by enzyme dissociation, accompanied by increased proteolysis, is an effective means of controlling the level of intermediates in propionic acid fermentation. Differential abilities of propionibacteria to fix CO2 could be associated (Wood and Leaver, 1953) with their abilities to carry out the reaction C02 Ci and to form sulfhydryl complexes with Ci. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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