Phosphatidylserine synthases

Kuge, O., and Nishijima M., 1997, Phosphatidylserine synthase 1 and 11 ofmammalian cells. Biochim. Biophys. Acta. 1348 151-156. 

Kuge, O., Salto, K., and Nishijima, M., 1997, Cloning of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylserine synthase (PSS) II, overexpression of which suppresses the phosphatidylserine biosynthetic defect of a PSS I-lacking mutant of CHO-Kl cells. J. Biol. Chem. 272 19133-19139... 

Kuge, O., Hasegawa, K., Saito, K., and Nishijima, M., 1998, Control of phosphatidylserine biosynthesis through phosphatidylserine-mediated inhibition of phosphatidylserine synthase 1 in Chinese hamster ovary cells. Proc. Natl. Acad. Sci. USA. 95 4199-4203. 

Stone, S.J., and Vance, J.E., 2000, Phosphatidylserine synthase-1 and -2 are locahzed to mitochondria-associated membranes. J. Biol. Chem. 275 34534-34540. 

VoeUcer, D.R., and Erazler, J.L., 1986, Isolation and characterization of a Chinese hamster ovary ceU line requiring ethanolamine or phosphatidylserine for growth and exhibiting defective phosphatidylserine synthase activity. J. Biol. Chem. 261 1002-1008. 

PHOSPHATIDYLSERINE SYNTHASE PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE SYNTHASE Phosphinate inhibitor,... 

Salomon Z, Lindblom G, Rilfors L et al (2000) Interaction of phosphatidylserine synthase from E. coli with lipid bilayers coupled plasmon-waveguide resonance spectroscopy studies. BiophysJ 78 1400-1412... 

Bailis, A.M., Poole, M.A., Carman, G.M., and Henry, S.A., 1987, The membrane-associated enzyme phosphatidylserine synthase is regulated at the level of mRNA abundance. Mol. Cell. Biol. 7 167-176. 

Kiyono, K., Miura, K., Kushima, Y., Hikiji, T., Fukushima, M., Shibuya, I., and Ohta, A., 1987, Primary structure and product characterization of the Saccharomyces cerevisiae CHOI gene that encodes phosphatidylserine synthase. J. Biochem. 102 1089-1100. 

Kodaki, T., Nikawa, J., Hosaka, K., and Yamashita, S., 1991b, Functional analysis of the regulatory region of the yeast phosphatidylserine synthase gene, PSS. J. Biochem. 173 7992-7995. 

Letts, VA., and Henry, S.A., 1985, Regulation of phospholipid synthesis in phosphatidylserine synthase-deficient (chol) mutants of Saccharomyces cerevisiae. J. Bacteriol. 163 560-567. 

Fig. 6. Synthesis of phospholipid polar head groups. The three major phospholipid species in E. coli are synthesized by a total of six different enzymatic activities (1) phosphatidate cytidylyltransferase (Cds), (2) phosphatidylserine synthase (PssA), (3) phosphatidylserine decarboxylase (Psd), (4) phosphatidyl-glycerol phosphate synthase (PgsA), (5) phosphatidylglycerol phosphate phosphatase (PgpA or PgpB), and (6) cardiolipin synthase (els).

Mouse Pss2 Phosphatidylserine synthase-2 Partial male infertility... 

Kelley, M.J., Badis, A.M., Henry, S.A. and Carman, G.M. (1988) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by inositol. Inositol is an inhibitor of phosphatidylserine synthase activity. J. Biol. Chem. 263, 18078-18085. 

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