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Phosphatidylinositol-4,5-bisphosphate PIP

Sequence of Events From Receptor to Protein Kinase Cyclic AMP (cAMP) and Phosphatidylinositol Bisphosphate (PIP )... [Pg.133]

Figure 11.21 Outline of synthesis of phosphatidylinositol, phosphatidylserine, phosphatidylethanolamine and phosphatidylcholine. Note in the synthesis of phosphatidylinositol, the free base, inositol, is used directly. Inositol is produced in the phosphatase reactions that hydrolyse and inactivate the messenger molecule, inositol trisphosphate (IP3). This pathway recycles inositol, so that it is unlikely to be limiting for the formation of phosphatidylinositol bisphosphate (PIP )- This is important since inhibition of recycling is used to treat bipolar disease (mania) (Chapter 12, Figure 12.9). Full details of the pathway are presented in Appendix 11.5. Inositol, along with choline, is classified as a possible vitamin (Table 15.3). Figure 11.21 Outline of synthesis of phosphatidylinositol, phosphatidylserine, phosphatidylethanolamine and phosphatidylcholine. Note in the synthesis of phosphatidylinositol, the free base, inositol, is used directly. Inositol is produced in the phosphatase reactions that hydrolyse and inactivate the messenger molecule, inositol trisphosphate (IP3). This pathway recycles inositol, so that it is unlikely to be limiting for the formation of phosphatidylinositol bisphosphate (PIP )- This is important since inhibition of recycling is used to treat bipolar disease (mania) (Chapter 12, Figure 12.9). Full details of the pathway are presented in Appendix 11.5. Inositol, along with choline, is classified as a possible vitamin (Table 15.3).
See also in sourсe #XX -- [ Pg.2 , Pg.178 ]

See also in sourсe #XX -- [ Pg.2 , Pg.119 , Pg.124 , Pg.125 , Pg.208 , Pg.217 , Pg.218 , Pg.226 , Pg.234 , Pg.236 , Pg.240 , Pg.241 ]

See also in sourсe #XX -- [ Pg.2 , Pg.174 ]



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