Phenylquinoxaline

Phenylquinoxaline behaves like 2,3-diphenylquinoxaline in giving a 1 1 1 molar adduct with the ester and methanol. The adduct is thought to possess structure (153) rather than the isomeric one (154). [Pg.164]

The reaction of o-diamines with w-nitroacetophenone in the presence of sodium dithionite furnishes 2-phenylquinoxalines, and reaction of o-phenylenediamine with p-N0..C,-.H4C0CH2X02 similarly gives 2- (4 -nitrophenyl) quinoxaline ... [Pg.208]

Phenylquinoxaline reacts with dimethyl acetylenedicarboxylate to give a product which after exposure to the atmosphere is isolated... [Pg.221]

Hydrogenation of 5,10-diazabenzo[6]biphenylene with Raney nickel in hot ethanol gave 2-phenylquinoxaline in 78% yield (9). Similar hssion of the four-membered ring occurs with biphenylene itself and with substituted bi-phenylenes (5). [Pg.175]

Benzenediamine (129) gave 2-phenylquinoxaline (132) [BzCH2SOMe or BzCH(SOMe)2, PhH, AcOH, reflux, 2 h 35% after separation from another product aerial or sulfoxide oxidation required with the first reagent). [Pg.22]

Benzenediamine (365) and 3-phenyl-4,5-dihydro-5-isoxazolone (366) gave 2-phenylquinoxaline (368), probably via the tetrahydro intermediate (367) (MeCN, reflux, 4 h 65%) " " several substituted-phenyl analogs were prepared similarly and in comparable yields." " When an unsymmetrically substituted benzenediamine was used, two isomeric products were expected, but only one could be detected in each such case tried." " ... [Pg.50]

Benzoxadiazole 1-oxide (490) gave either 2-phenylquinoxaline 4-oxide (491) [PhCH=CHC(=0)Me, HN(CH2)4, MeCN, reflux, 24 h 35% note deacylation] or 2-acetyl-3-phenylquinoxalme 4-oxide (492) [PhCH - -... [Pg.65]

Reduction of unsubstituted benzo[3,4]cyclobuta[l,2-/7]quinoxaline (526) with Raney nickel in refluxing ethanol during 30 min gave 2-phenylquinoxaline (527) in... [Pg.71]

Methoxy-3-phenylquinoxaline and benzaldehyde gave a separable mixture of 5-(a-hydroxybenzyl)-2-methoxy-3-phenyl- (42) and 5-(a-hydroxybenzyl)-3-methoxy-2-phenylquinoxaline (43) [LiN(CMe2CH2)2CH2 (made in situ). [Pg.101]

Crystal Structures. Crystal structures have been determined by X-ray analysis for the following simple alkyl- or arylquinoxalines 2-phenylquinoxaline ... [Pg.116]

Chloro-8-methyl-5-nitro-2-phenylquinoxaline (102, R = Cl) gave 5-methyl-7-methylamino-8-nitro-3-phenylquinoxaline (102, R = NHMe) (MeNH2, H2O-EtOH, reflux, 4h 93%) the isomeric 5-methyl-7-methylamino-8-nitro-2-phenylquinoxalme was made similarly in 95% yield. ... [Pg.152]

Acetyl-3-chloro-2-phenylquinoxaline gave 6-acetyl-2-phenyl-1,2,3,4-tetrahy-droquinoxaline (185) [H2 (3 atm), Pd/C, EtsN, EtOH, 20°C, 2h 85% note nuclear reduction] and thence 6-acetyl-2-phenylquinoxaline (H2O2, HCl, MeOH, 20°C, 40 min 69%). ... [Pg.168]

The kinetics for alkaline hydrolysis of 2-(o-, m-, or -nitrophenoxy)quinoxaline to 2(171)-quinoxalinone have been measured in some detail. 6,7-Dimethoxy-2-phenylquinoxaline (17) gave 2-phenyl-6,7(l//,4//)-quinoxaline-dione (18) (48% HBr, reflux, 23 h 53% as hydrobromide). [Pg.191]

Note. Such derivatives of quinoxaline ketones are not encountered as often as those of quinoxalinecarbaldehydes, but a few examples can be given here. 6-Acetyl-2-phenylquinoxaline gave its oxime, 6-[l-(hydroxyimino)ethyl]-2-phe-nylquinoxaline (209) (H2NOH HCl, NaOH, EtOH, H2O, reflux, 2 h 75%). ... [Pg.354]

See also in sourсe #XX -- [ Pg.175 ]

See also in sourсe #XX -- [ Pg.22 , Pg.50 , Pg.51 , Pg.56 , Pg.71 , Pg.106 , Pg.127 , Pg.219 , Pg.231 , Pg.354 ]

See also in sourсe #XX -- [ Pg.22 , Pg.50 , Pg.51 , Pg.56 , Pg.71 , Pg.106 , Pg.127 , Pg.219 , Pg.231 , Pg.354 ]

See also in sourсe #XX -- [ Pg.18 , Pg.261 ]

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