Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Phenyl lactate

Phenylpyruvate can be reduced to phenyl lactate and oxidatively decarboxylated to phenylacetate. both of which are also excreted in the urine. [Pg.455]

In the first, the sodium acetate unites with the aldehyde, forming sodium phenyl lactate ... [Pg.285]

CTB. Teplyakov, A., Wilson, K. S., Orioli, P, Mangani S., The High Resolution Structure of the Complex between Car-boxypeptidase A and L-Phenyl Lactate. To be published. [Pg.1188]

Phenylketonuria is due to an inborn error of phenylalanine metabolism. Typically, it is due to a deficiency of phenylalanine hydroxylase (which converts phenylalanine to tyrosine). Less commonly it is caused by a deficiency of dihydrobiopterin reductase and a resulting inability to synthesize biopterin. All these conditions cause an accumulation of phenylalanine this can be transaminated to phenylpyruvate which is converted to phenyl lactate and phenyl acetate. [Pg.467]

Fig. 14-47 Conversion of phenylpyruvate (A) via phenyl lactate (B) to phenyl acetate (C). Fig. 14-47 Conversion of phenylpyruvate (A) via phenyl lactate (B) to phenyl acetate (C).
Fig. 16.12 Chromatogram of organic acids extracted using DEAE-Sephadex from the urine of a patient with untreated classical phenylketonuria, separated as their ethoxime and trimethylsilyl derivatives on 10 per cent OV-101 on HP Chromosorb W (80-100 mesh) by temperature programming from 110°C to 285°C at 4°C min" with a 5 min initial isothermal delay. Peak identifications are 1, sulphate 2, benzoate 3, phosphate 5, mandelate 6, 2-hydroxyphenylacetate 7, phenyl-lactate 8, phenylpyruvate 9, hippurate 10, citrate 11, 4-hydroxyphenyl-lactate 12, 4-hydroxyphenylpyruvate 13, undecanedioate (internal standard) 14, urate 15, indole-3-lactate 16.5-hydroxyindole-3-acetate 17, n-tetracosane (standard) 18, -hexacosane (standard). The position of phenylacetate is arrowed (peak 4) but free phenylacetate has never been observed by the authors in the urine of untreated phenylketonuric patients. (From Chalmers, 1974). Fig. 16.12 Chromatogram of organic acids extracted using DEAE-Sephadex from the urine of a patient with untreated classical phenylketonuria, separated as their ethoxime and trimethylsilyl derivatives on 10 per cent OV-101 on HP Chromosorb W (80-100 mesh) by temperature programming from 110°C to 285°C at 4°C min" with a 5 min initial isothermal delay. Peak identifications are 1, sulphate 2, benzoate 3, phosphate 5, mandelate 6, 2-hydroxyphenylacetate 7, phenyl-lactate 8, phenylpyruvate 9, hippurate 10, citrate 11, 4-hydroxyphenyl-lactate 12, 4-hydroxyphenylpyruvate 13, undecanedioate (internal standard) 14, urate 15, indole-3-lactate 16.5-hydroxyindole-3-acetate 17, n-tetracosane (standard) 18, -hexacosane (standard). The position of phenylacetate is arrowed (peak 4) but free phenylacetate has never been observed by the authors in the urine of untreated phenylketonuric patients. (From Chalmers, 1974).

See other pages where Phenyl lactate is mentioned: [Pg.1298]    [Pg.1298]    [Pg.65]    [Pg.31]    [Pg.687]    [Pg.1305]    [Pg.455]    [Pg.65]    [Pg.285]    [Pg.1060]    [Pg.389]    [Pg.46]    [Pg.407]    [Pg.112]   
See also in sourсe #XX -- [ Pg.452 ]




SEARCH



© 2024 chempedia.info