Diethyl phenyl orthoformate

The Grignard reaction has been improved by the use of phenyl diethyl orthoformate, which may be prepared by an ester exchange reaction between equimolar amounts of triethyl orthoformate and phenol.113... 

Diethyl phenyl orthoformate (diethoxy phenoxy ethane) [14444-77-0] M 196.3, b... 

Another work of Duhamel and Ancel [59] related this synthesis of retinal via (3-ionylideneacetaldehyde. Condensation of methallyl-magnesium chloride with diethyl phenyl orthoformate (EtC CHOPh) led after bromination of the ene-acetal, deshydrohalogenation (NaOH 50%), ethanol elimination with hexamethyldisilazane (HMDS) and ISiMes, to the bromo-dienol ether. This latter was submitted to bromine lithium exchange and the lithio enol ether was then condensed with p ionylideneacetaldehyde to give retinal, Fig. (28). 

Diethyl phenyl orthoformate (diethoxy phenoxy ethane) [14444-77-0] M 196.3, b lll Vllmm, 122°/13mm, d20 1.0099, n2D° 1.4799. Fractionated through an efficient column under vacuum [Smith Acta Chem Scand 10 1006 7956]. 

ALDEHYDES 9-Borabicyclo[3.3.1]-nonane. Diazoacetaldehyde. Diethyl-allylthiome thylphosphonate, Diethyl phenyl orthoformate Dithiane. Lith-ium-Alkylamine. Lithium diisopropyl-amide. Sodium tetracarbonylferrate-(TI). 1,1,3,3-Tetramethylbutylisonitrile. 2,4,4,6-Tetramethyl-5,6-dihydro-l, 3-(4H)-oxazine. Triethylsilane. s-Trithiane. 

Nitro compounds, ar. Nitrobenzene, m-Dinitrobenzene o Nitrophenol N-Nitramines Oxonium fluoroborate Trialkyloxonium salt T rialkyloxonium fluoroborate Pyrylium fluoroborate Carboxylic acid esters HCOOC2HS, p-Nitro-phenyl formate Isopropenyl acetate Ethyl cyanoacetate Chloroformic acid esters Ethyl chloroformate Methyl trichloroacetate Diethyl oxalate Ethyl malonate Orthoformic acid esters, Ethyl orthoformate (RC0)20 (CHsC0)20,... 

Related Reagents. Diethyl Phenyl Orthoformate Dimethoxy-carbenium Tetrafluoroborate Dimethylchloromethyleneammo-nium Chloride Ai,Ai-Dimethylformamide A, A -Dimethyl-formamide Diethyl Acetal Methyl Formate. 

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