Phencyclidine 3-Phenethylamines

Both indoleamine (e.g., lysergic acid diethylamide, LSD psilocybin) and phenethylamine hallucinogens (e.g., mescaline) increased pupil diameter.26 There have been no systematic studies of the effects of these drugs on dynamic measures of the light reflex. Phencyclidine (PCP) does not cause marked changes in pupil size or light reflex. However, subjects intoxicated with PCP often show horizontal and vertical nystagmus.26... 

Subsequently, Purdie and coworkers studied the CD induced in phencyclidine (and its pyrrolidine and morpholine analogues), 6-phenethylamine, phenobarbital, meperidine HC1, diazepam, and dilantin by 6-cyclodextrin [59], In this work, a method was described for the assay of meperidine in commercially available Demerol tablets. The complexation between 6-cyclodextrin and eight 5,5-disubstituted derivatives of barbituric acid was characterized on the basis of the... 

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