Phenanthridines synthesis

X-ray crystal structure, 6, 516 Benzophenanthridines synthesis from anils, 2, 416 Benzophenanthridines, tetrahydro-synthesis, 2, 469 Benzo[c]phenanthridines synthesis, 2, 414 from aryl isocyanides, 2, 411 from benzynes, 2, 432 Benzo[i]phenanthridines synthesis, 2, 414 Benzophenanthridinones... 

Phenanthridine synthesis.2 Treatment of the haloanil (1) with potassium amide in liquid ammonia gives phenanthridine (2) in > 90% yield. A benzyne intermediate is... 

The amino group can then direct lithiation at 2 position and lead to a carbon substituent (like COOH or CHO) and lead to a phenanthridine synthesis. 

A more recent synthesis via the 2-aryl-l-tetralone intermediate developed by Janin and Bisagni (93T10305) provides a route to the benzo[c]phe-nanthrid-6(5//)-ones and 6-chlorobenzo[c]phenanthridines. Synthesis of... 

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