Phase-separable catalysis, thermoregulate

The opposite temperature-dependent solubility of ligands in organic solvents is applied in the thermoregulated phase-separable catalysis (TRPSC) first published by Jin and coworkers [17] in 2000. The general principle is shown in Fig. 2 [10]. 

Fig. 2 The general concept of thermoregulated phase-separable catalysis (TRPSC)...

Thermoregulated phase-transfer and phase-separable catalysis are attractive catalyst recycUng techniques complementing other approaches of multiphase catalysis. They utilize temperature-dependent solubility or miscibiUty phenomena to switch between homogeneous reaction and heterogeneous separation stages. 

Thermoregulated Phase-transfer and Thermoregulated Phase-separable Catalysis... 

Yu, F. Zhang, R. Xie, C. Yu, S. (2010). Polyether-substituted thiazolium ionic liquid catalysts - a thermoregulated phase-separable catalysis system for the Stetter reaction. Green Chem. Vol. 12, No. 7, pp. 1196-1200, ISSN. 1463-9262... 

Recently, a new aqueous biphasic catalytic system based on the cloud point of nonionic tensioactive phosphine, termed thermoregulated phase-transfer catalysis (TRPTC) has been developed [13]. The concept ofTRPTC as a missing link could not only provide a meaningful solution to the problem of catalyst/product separation, but also extricate itself from the limitation of low reaction rates of water-immiscible substrates. 

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