Phase N-alkylation

The vapor phase N-alkylation of aniline with ethanol took place over an H-ZSM-5 catalyst at temperatures between 250° and 500°C. The maximum selectivity for N-monoethylation occurred at the lower temperatures with increasing amounts of diethyl aniline produced at higher reaction temperatures. v/ith montmorillonite catalyst, reaction at 400°C gave a 64% selectivity for N-ethyl aniline formation at 77% conversion. A vanadium exchanged montmorillonite was more active but less selective giving N-ethyl aniline in 48% selectivity and N, N-diethyl aniline in 37% selectivity at 97% conversion.94... 

VAPOR-PHASE N-ALKYLATION OF IMIDAZOLES WITH ALCOHOLS OVER ZEOLITES... 

Figure 6, Comparative gas-phase N-alkylation of a chiral amine and its corresponding racemic mixture.

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