Pharmacokinetic Basis for PCA

SECTION 4 Drugs Used to Treat Pain and Inflammation 

FIGURE 17-1 Pharmacokinetic model for PCA using opioid drugs. Conventional intramuscular injection is indicated by the long solid lines, PCA is indicated by the short dashed lines, and the therapeutic window for analgesia is indicated by the shaded area. CFrom Ferrante, et at Anesth Analg. 1988 67 457-461 with permission.) 

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