Pharmaceuticals phenylpropanoids

Analytical TLC differs from PLC in that larger weights and volumes of samples are applied as a band across the entire layer width to thicker (0.5-2 mm) and sometimes larger layers, the purpose of which is the isolation and purification of 10-1000 mg of sample for further analysis. Multiple development of the plate is commonly used, and the separated substances are detected by a non-destructive method (e.g., under UV light and iodine vapors), and recovered by extraction from scraped layer material. PLC can be used to isolate sufficient pure drug compounds for confirmation by spectrometry in cases where analytical TLC is not adequate for identification. Examples of pharmaceutical applications of PLC include a new sesquiterpene trimer and phenylpropanoid glycosides. ... 

Sugimoto N, Goto Y, Akao N, Kiuchi F, Kondo K, Tsuda Y. Mobility inhibition and nematocidal activity of asarone and related phenylpropanoids on second-stage larvae of Toxocara. Biol Pharmaceut Bull 1995 18 605-9. 

Isoflavonoids are a class of plant natural products gaining attention due to their pharmaceutical properties. These natural compounds constitute a subclass of flavo-noids, which belong to a broader class of plant products known as phenylpropanoids. 

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