Formulation pharmaceutical

The dihydrochloride is a white crystalline powder, m.p. about 225 C (decomp.). Used as an antiseptic and skin sterilizing agent, and as a bacteriostat in some pharmaceutical formulations. 

Quantitative voltammetry has been applied to a wide variety of sample types, including environmental samples, clinical samples, pharmaceutical formulations, steels, gasoline, and oil. 

Description of Method. The amount of chlorpromazine in a pharmaceutical formulation is determined voltammetrically at a graphite working electrode in a nonstirred solution. Calibration is achieved using the method of standard additions. 

USP-grade anhydrous magnesium carbonate is used as a flavor impression intensification vehicle in the processed food industry (see Flavors and spices). Basic magnesium carbonates are used as free flowing agents in the manufacture of table salt, as a hulking agent in powder and tablet pharmaceutical formulations, as an antacid, and in a variety of personal care products (see Pharmaceuticals). 

The field of steroid analysis includes identification of steroids in biological samples, analysis of pharmaceutical formulations, and elucidation of steroid stmctures. Many different analytical methods, such as ultraviolet (uv) spectroscopy, infrared (ir) spectroscopy, nuclear magnetic resonance (nmr) spectroscopy, x-ray crystallography, and mass spectroscopy, are used for steroid analysis. The constant development of these analytical techniques has stimulated the advancement of steroid analysis. 

Diclofenac is an exceedingly potent COX inhibitor slightly more efficacious against COX-2 than COX-1. Its absorption from the gastrointestinal tract varies according to the type of pharmaceutical formulation used. The oral bioavailability is only 30-80% due to a first-pass effect. Diclofenac is rapidly metabolised (hydroxylation and conjugation) and has a plasma half-life of 1.5 h. The metabolites are excreted renally and via the bile. 

The Cassia angustifolia GaM possesses the potential to become a new source of commercial gum due to its high content in the endosperm (about 50%) and its valuable rheological properties. It was suggested, in a similar way as for other GaMs, for usage as an additive in pharmaceutical formulations [188, 246]. Also the Ipomoea seed gum in its natural form, and after modification by grafting, has the potential to be used as a commercial gum [178]. 

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