Peterson reaction, organolithium reagents

Preparation of 2-substituted a-Alkenes. The reaction of trimethylsilylacetone with Grignard and organolithium reagents has been employed in the synthesis of 2-substituted propenes via the formation of a /3-hydroxysilane, which is then subjected to a Peterson elimination (eq 1). It was also used to prepare, y-unsaturated esters, nitriles, and amides (eq 2). ... 

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