Peripherally Modified Dendrimers in Asymmetric Catalysis

In contrast to the core-functionalized systems, periphery-functionalized dendrimers have their catalytically active groups located at the surface of the den- 

The first example of a catalytically active metallodendrimer, having catalytic groups at the periphery, was reported by van Koten, van Leeuwen and coworkers [20]. These authors prepared the nickel(II) complexes containing carbosilane dendrimers, which were successfully employed in the homogeneous regioselective Kharasch addition of polyhalogenoalkanes to the terminal C=C double bonds. Since these early studies there has been a steadily increasing number of dendrimer catalysts which have been synthesized and studied [15]. In this section, the details of peripherally modified chiral dendrimer catalysts for different asymmetric catalytic reactions will be summarized. 

By using commercially available zero- to fourth-generation poly(propyleneimine) 

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