Periodic review

Thus the ADI in mg per kg per day is an estimate of the daily pesticide dietary intake that appears to be without risk over the entire human lifetime. ADI values are estabHshed and periodically reviewed by joint committees of the Eood and Agricultural Organization (EAO) and WHO of the United Nations. 

The safety status of the process should be periodically reviewed against the guiding principles for the original design. Monitoring of add-ons can detect potentially dangerous modifications. Process hazards analysis or process safety audits are useful tools for this review. Documentation of inherently safer principles is critical to ensure that future changes don t nullify the positive features of the initial installation. 

Once adopted, plans should be periodically reviewed (depending on the project) and evaluated for effectiveness and cost/benefit. If the scope of work or any worksite hazards change significantly or if lessons learned indicate a review, the plans should be revised promptly... 

The next topic to address is the process of setting OELs. The rationale for setting OELs has no basis in absolute information, and the procedure to be followed may differ from country to country and from substance to substance. Scientific criteria for health protection should be used in combination with considerations of their technical and economic feasibility in a dynamic process in which the development of scientific knowledge underlies rapid changes entailing the need to periodically review the data. 

Do executive management establish the continuing suitability and effectiveness of the quality system through periodic reviews ... 

Conduct periodic reviews of your policies and objectives. 

Conduct periodic reviews of the quality system using the collected data. 

Document maintenance, keeping them current, periodic review... 

Subcontractor/supplier performance will be evident from audit reports, surveillance visit reports, and receipt inspections carried out by you or the third party if one has been employed. You need to examine these documents for evidence that the subcontractor s quality system is controlling the quality of the products and services supplied. You can determine the effectiveness of these controls by periodic review of the subcontractor s performance what some firms call vendor rating . By collecting data on the performance of subcontractors/suppliers over a long period you can measure their effectiveness and rate them on a scale from excellent to poor. In such cases you should measure at least three characteristics quality, delivery, and service. Quality would be measured by the ratio of defective conforming products received delivery would be measured by the number of days early or late and service would be measured by the responsiveness to actions requested by you on scale of excellent to poor. The output of these reviews should be in the form of updates to the list of assessed subcontractors/suppliers. 

The standard requires training effectiveness to be periodically reviewed with special attention given to customer-specific requirements. 

The facility periodically reviews its compliance status to assure that the programs which have been implemented are operating as designed. 

Process risk management Industrial hygiene risks should be periodically reviewed as are process safety risks. Some of the process hazard assessment techniques used for PSM can be expanded to include consideration of industrial hygiene issues... 

How are potential litizards recognized (This can be detennined by periodic review of hazards and prevention measures.)... 

A periodic review of ongoing water treatment programs with regard to suitability, economic benefit, training needs, and technical objectives also is required. 

Are SOPs periodically reviewed and updated Is training performed after the updates ... 

Periodically review patient data for consistency with diagnostic criteria, and regularly monitor changes in symptomatology. 

The codes and standards are drawn up by committees of engineers experienced in vessel design and manufacturing techniques, and are a blend of theory, experiment and experience. They are periodically reviewed, and revisions issued to keep abreast of developments in design, stress analysis, fabrication and testing. The latest version of the appropriate national code or standard should always be consulted before undertaking the design of any pressure vessel. 

Changes to methods will occur due to changes in applications and technological developments and these changes need to be formally implemented and recorded, after appropriate validation. A periodic review (commonly every two years) and, where necessary, revision is considered to be good practice . 

Material Safety Data Sheets, describing hazards and precautionary measures, have been produced for an equal period. Reviews of new products prior to commercialization have been mandatory in our company well before PMN rules appeared. 

New syntheses of /> ra-carborane, 1,12-C2B10H12, and derivatives have not been reported in the literature in the period reviewed. However, many reactions of the commercially available /vzra-carborane and their derivatives have been published and only cage C-H to C-X and B-H to B-X conversions are listed in Table 25 (COMC (1982) 5.4.2.7... 

The chemistry of aromatic heterocycles has been exhaustively reviewed in a book,55 and discussions of aromatic heterocycles are compiled in a few monographs on heterocyclic systems.13 Starting from 1979 to date, the literature related to heterocyclic chemistry, including heteroaromatics, is periodically reviewed by Belen kii and co-workers in Advances in Heterocyclic Chemistry,56-59 while earlier surveys were published by Katritzky and co-workers.60 61 Two multivolume treatises of Comprehensive Heterocyclic Chemistry, published in 1984 and 1996, have thoroughly reviewed all heterocyclic systems, including heteroaromatics, and relevant chapters are cited throughout this review. 

Although the US is one of the few countries to have a formal system for monitoring adverse reactions from food additives as part of its regulatory structure, other countries also periodically review additives. In addition, the Food and Agriculture Organization (FAO) of the United Nations and the World Health Organization (WHO) also monitors food additives. Since 1956, the Joint FAO/WHO Expert Committee on Food Additives has developed specifications for the purity of additives, evaluated toxicological data, and recommended safe levels of use. 

From the results published in the period reviewed in the present work there is no relevant novelty as regards the structure of amino, nitroso and nitro groups. 

Feature 3. Assess vulnerabilities and periodically review and update vulnerability assessments to reflect changes in potential threats and vulnerabilities. 

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