Percutaneous exposures miosis

If liquid/droplet exposure is known or suspected in an individual exhibiting miosis only or miosis and rhinorrhea only, it is recommended that the individual receive no antidote treatment but be closely observed for at least 18 h given that toxic effects of liquid percutaneous exposure may not manifest for several hours (Sidell, 1997 Cannard, 2006). Toxic effects from vapor-only exposure usually occur quickly (within minutes Sidell, 1997). Current... 

Local irritations do not occm except by fasciculation of xmderlying muscles after percutaneous uptake or miosis caused by excessive stimulation of muscarinic receptors on the papillary sphincter muscles, resulting from ocular exposure (Sidell and Borak, 1992 Dabisch et al., 2008). However, clinical symptoms related to massive restraints in motoric and respiratory abilities require the reduction of AChE activity by more than... 

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