Peptides literature conclusions

IMS-MS applications published in the literature can be grouped into two categories. The first contains studies of conformations of flexible molecules. Such flexible molecules include synthetic polymers and biopolymers such as peptides, proteins, and oligonucleotides. The studies of the second category deal with the geometry of cluster ions such as carbon clusters, semiconductor clusters, metal clusters, salt clusters, ion-ligand clusters. The major conclusions regarding structure of these systems are reviewed in Sect. 5. 

As a conclusion, it can be stated that the use of adequate model peptides allows one to obtain information on the molecular dynamics of the peptide chain by means of fluorescence techniques. Both conformational and configurational effects have to be taken into account when analyzing the photophysics of these aromatic peptides. Moreover, rate constants and thermodynamic parameters of conformational transitions can be obtained. Until now, no other technique offers the possibility to obtain quantitative information on the molecular dynamics of peptides and, to our knowledge, no other reports on the rate of conformational transitions of peptides can be found in literature. 

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