Peptide basic biochemistry

This section begins with a general discussion of the basic biochemistry of peptides and proteins followed by discus-... 

Horsthemke B, Bauer K (1982) Substrate specificity of an adenohypophyseal endopeptidase capable of hydrolyzing LHRH preferential cleavage of peptide bonds involving the carboxyl terminus of lower of it of hydrophobic and basic amino acids. Biochemistry 21 1033-1036 Horsthemke B, Knisataschek H, Rivier J, Sandow J, Bauer K (1981) Degradation of LHRH and analogs by adenohypophyseal peptidases. Biochem biophys Res Commun 100 753-759... 

Ttlchsen E, Woodward C (1987) Assignment of asparagine-44 side-chain primary amide. N NMR resonances and the peptide amide. N H resonance of glycine-37 in basic pancreatic trypsin inhibitor. Biochemistry 26 1918-1925... 

In order to understand the biochemistry of mercury more completely, it is important to describe the chemistry of this element with sulfhydryl donors in the most common coordination environments. Ideally, one would examine mercuric complexes within a construct that was basically invariant, but which allowed for preparation of mercury compounds in the most common structures. The desired coordination modes include linear (or slightly bent) for 2-coordinate complexes, trigonal planar (or slightly T-shaped) for 3-coordinate compounds and tetrahedral for 4-coordinate complexes. Figure 1. Unfortunately, diere are no known native systems that allow for this diversity of metal coordination geometry. However, given advances in peptide synthesis and the prediction of... 

Hileman RE, Jennings RN, Linhardt RJ. Thermodynamic analysis of the heparin interaction with a basic cyclic peptide using isothermal titration calorimetry. Biochemistry 1998 37 15231-15237. 

HPLC and gas chromatography combination of the above were the basic tools of biochemistry combined with structural analysis sequencing of first simple RNA viruses peptide sequencing... 

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