Penthrane - Methoxyflurane

Methoxyflurane (Penthrane), a volatile liquid, provides analgesia and anesthesia It is usually used in combination with nitrous oxide but may also be used alone. It does not produce good muscle relaxation, and a skeletal muscle relaxant may be required. 

Figure 7.1.8 The molecular structure of methoxyflurane (penthrane or metofane).

Methoxyflurane is an extremely powerful inhalation anesthetic that is an excellent skeletal muscle relaxant. However, its use is somewhat limited by its relatively high solubility, which causes the patient to make a slow transition back into consciousness. Another disadvantage of methoxyflurane is that fluorine ions are the product of its biotransformation, which may lead to the development of renal failure. Therefore, it is recommended to use methoxyflurane for anesthesia during interventions of no more than 2 h. A very common synonym for methoxyflurane is penthrane. 

Parenteral 0.5, 2.5, 5 g powder to reconstitute for injection Methoxyflurane (Penthrane)... 

Desflurane [Suprane] Enflurane [Ethrane] Halothane [Fluothane] Isoflurane [Forane] Methoxyflurane [Penthrane] Sevoflurane [Ultane]... 

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