2.4- Pentanedione Subject

Comprehensive work in this field has been done by Slovak authors (98MI1, 95M1359, 96CCC269, 96CCC371, 97CCC99). They prepared 2-substituted (H, Me, Ph) 4-, 5-, 6-, and 7-nitrobenzoxazoles, which were then reduced to amines (not isolated) and subjected to subsequent nucleophilic substitution with activated enol ethers such as alkoxymethylene derivatives of malonic acid esters and nitrile, 3-oxobutanoic acid esters, pentanedione, or cyanoacetic acid esters to yield aminoethylenes 8. 

Smith et al (84) determined hydralazine in tablets. An aqueous extract of the tablets was treated with 2,4-pentanedione, forming 1-(3,5-dimethylpyrazole) phthalazine. The method was applied to stability studies of tablets subjected to elevated temperatures, where tablets could not be analyzed by the USP method. 

All ligands receive a separate subject entry, e.g., 2,4-Pentanedione, iron complex. The headings Ammines, Carbonyl Complexes, Hydride complexes, and Nitrosyl complexes are used for the NH, CO, H, and NO ligands. 

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