Pellagra Psychiatric Manifestations

Psychiatric manifestations are fairly common but are easily overlooked due to their non-specific nature. These are commonly seen as irritability, poor concentration, anxiety, fatigue, restlessness, apathy and depression. The occurrence of psychosis in pellagra is an uncommon finding, especially as an early feature and we have described it under a separate heading. Additionally, the psychotic spectrum is usually seen in advanced stages of pellagroid encephalopathy, commonly found in chronic alcoholics (Cook et al. 1998). 

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