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Pegylated polymers chains

Dai et al. have developed nanosized, reduced 20 nm graphene oxide (nano-rGO) sheets functionalised non-covalently by amphiphilic PEGylated polymer chains (432) with high near-infrared (NIR) light absorbance and biocompatibility for potential photothermal therapy. In the absence of any NIR irradiation, nano-rGO exhibited little toxicity in vitro at concentrations well above the doses needed for photothermal heating. ... [Pg.136]

Polyethylene glycol (PEG) consists of repeating units of ethylene glycol forming linear or branched polymers with different molecular masses. Pegylation is the process by which PEG chains are covalently attached to lEN molecules. Pegylation confers a number of properties on lEN-a molecules, such as sustained blood levels that enhance antiviral effectiveness and reduce adverse reactions, as well as a longer half-life and improved patient compliance (Kozlowski et al. 2001). [Pg.212]

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