Paul and Joyce

Figure 7.10 Coiled-coil structures during peptide condensation, (a) Two peptides containing heptad repeats (A to F and A to F ) able to form a-helices. Hydrophobic interactions (A-A and D-D ) lead to coiled-coil structures, (b) A full-length peptide (T) acts as a template forming a coiled-coil structure with peptide fragments and directing their condensation in other full-length peptides (B). (Adapted from (a) Paul and Joyce, 2004 (b) Ghosh and Chmielewsld, 2004.)...

How realistic is all this One may recall at this point the previously mentioned self-replicating ribozyme reported by Paul and Joyce (2002) - however, we are still far from the production of an RNA polymerase that catalyzes the synthesis of itself as well as the synthesis of another ribozyme. 

Paul, N. and Joyce, G. F. (2002). A self-replicating ligase ribozyme. Proc. Natl. Acad. 

Glover, Jonathan. 1970. Responsibility. London Routledge and Kegan Paul. Gold, Mark S., and Norman S. Miller. 1997. "Cocaine (and Crack) Neurobiology." In Substance Abuse A Comprehensive Textbook, edited by Joyce H. Lowinson, Pedro Ruiz, Robert B. Millman, and John G. Langrod. Baltimore, Md. Williams and Wilkins. 

In gathering material for this article, I would like to express my deepest appreciation to all those individuals who kindly shared their knowledge of Henry Francis du Pont and Winterthur as it developed over the years, especially John Sweeney, George Colman, Everett Boyce, Charles Hummel, Mrs. Edmond du Pont, and Mrs. Leslie Potts. Also I would like to acknowledge the kind assistance of Barbara Hearn, former Museum Archivist Paul Hensley, current Museum Archivist Catherine Hutchins, Associate Editor, Publications Office Ann Clapp, former Paper Conservator Joyce Hill Stoner, Director, Winterthur-University of Delaware Program in Conservation of Artistic and Historic Objects and Mrs. Charles Montgomery, former Assistant Curator of Textiles. 

We thank John Bendler for performing the molecular modeling calculations and for many helpful discussions. Monty Alger and Lorraine Rogers provided some of the permeability data, while John Campbell, Dave Dardaris, Gary Faler, Ed Fewkes, Paul Howson, Rick Joyce, Jerry Lynch and John Maxam contributed to the results described in this report. 

See, for example, Paul B. Armstrong, Play and the Politics of Reading The Social Uses of Modernist Form (Ithaca, NY and London Cornell University Press, 2005) David Ellison, Ethics and Aesthetics in European Modernist Literature Prom the Sublime to the Uncanny (Cambridge Cambridge University Press, 2002) Lee Oser, The Ethics of Modernism Moral Ideas in Yeats, Eliot, Joyce, Woolf, and Beckett (Cambridge Cambridge University Press, 2007). 

This work was partially supported by NIH grant GM45811. We thank Steve Harvey, Gerry Joyce and Jayashree Srinivasan for many useful comments, and Paul Beroza, Doree Sitkoff, Jarrod Smith and Neill White for serving as code testers, and for contributing to the code and documentation. 

T. S. Eliot, Ulysses, Order and Myth, in James Joyce The Critical Heritage, ed. R. Deming, vol. I (New York Routledge Kegan Paul, 1970), pp. 268-71. Mythistorema, 3 (the poem is untitled). 

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