Pattern recognition electronic factors

Henry, D. R. Lavine, B. K. Jurs, P. C. Electronic factors and acridine frameshift mutagenicity—a pattern recognition study. Mutat. Res. 1987, 179, 115-121. 

In eq 24, PI5Q = -log I50 where I is the molarity causing 50% inhibition, n is the number of carbon atoms in an alkyl chain, A is an electronic factor, B a hydrophobic parameter, and C is the contribution to activity of the parent portion of the molecule. Amoore i continues to make progress in quantitatively correlating the shape of organic compounds with their odor. The similarity of molecules is compared by scanning their molecular silhouettes with a computerized pattern recognition machine. 

In recent years there has been an explosive growth in the study of transition metal cluster compounds. Many factors have contributed to this growth -- the development of preparative and separative procedures, the expectation that cluster compounds mimic catalytic metal surfaces and so may provide insights into catalytic mechanisms (as well as, potentially, being catalysts themselves), the development of new techniques by which metal surfaces - and species absorbed onto them -may be studied, the recognition that novel bonding patterns may exist within them, and their involvement in bioinorganic chemistry, particularly as electron sinks and sources. 

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