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Pathophysiology of BOS

Clinic Coarse crackles, increased sputum production No crackles, no sputum [Pg.549]

Time of onset Early after transplantation ( 1 yr) Later ( 1 yr) [Pg.549]

Histology Inflammatory, ends up in fibrosis Pure fibrosis ( ) [Pg.549]

Radiology Airway wall thickening, mucus plugging, bronchiectasis Air trapping, consolidation [Pg.549]

Effect of azithromycin Improvement of FEVi (reversible) No effect on FEVi (irreversible) [Pg.549]


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Pathophysiological

Pathophysiology

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