Paracyclophane ketimines

In addition, we investigated a nonlinear-like effect (NLE), activity, temperature dependence, and kinetics of hydroxy[2.2]paracyclophane ketimine ligands with the 1,2-addition reaction of diethylzinc to cyclohexylcarbaldehyde. A linear correlation between the enantiomeric excess of AHPC ketimine ligands bearing a phenylethyl side group and the product was observed with 0.5 mol% of catalyst loading. When the catalyst loading of (Sp,S)/(Rp,R)-4a was increased to 4 mol%, a precipitate of the inactive heterochiral species was formed and resulted in a positive nonlinear like effect (Fig.2.1.3.6), while a linear behavior is observed with 5b (Fig. 2.1.3.7). The enantiomeric ratio was found to have linear temperature dependence. [16]... 

The second generation of N,0-[2.2]paracyclophane ketimine ligands (Rp,S)-5b, 6b were investigated for their ability to catalyze the 1,2-addition of alkenylzinc... 

Wamke I, Ay S, Brase S, Furche F (2009) Chiral cooperativity and solvent-induced tautom-erism effects in electronic circular dichroism spectra of [2.2]paracyclophane ketimines. J Phys Chem A 113 6987-6993... 

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