Pancreatic gland material

Figure 2. Diagrammatic representation of a pancreatic exocrine cell. Secretory precursor proteins are synthesized by the RER and sequestered in the cisternae of that organelle (1). The material is then transferred by way of small vesicles to mature Golgi saccules and vacuoles (2). Within the vacuoles the secretory precursors are concentrated with the removal of water (3) and the Golgi vacuole is transformed into a mature zymogen granule (4). In response to the appropriate stimulus, the membrane of the zymogen granule fuses with the apical plasma membrane (5), and the final secretory product is released to the lumen of the gland.

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