Paederia scandens

It has been shown that 7-deoxyloganic acid (81) is a precursor of various iridoglucosidesFeeding experiments on the plants Gardinia jasminoides and Paederia scandens have shown that the acid is incorporated into the irido-glucosides of these plants and a biogenetic scheme is proposed. ... 

A. and the listed compounds occur mainly in Rubia-ceae but have also been detected in other plant families. A. is isolated from fresh woodruff Asperula odorata) and the bark of the New Zealand plants Co-pro strut robusta (1.2%), C. tenuifolia (2.9%), C. repens (1.7%), and C. arborea (0.6%) (all Rubiaceae). Paederoside and paedetosidic acids occur in the Japanese plant Paederia scandens (Rubiaceae). In the paederoside compounds the acetate group of A. is replaced by 5-methylthiocarbonate these are as yet the only known sulW-containing iridoid glucosides and appear to be the main cause of the unpleasant smell of Paederia species. 

The aphid Acyrsiphon nipponicus secretes paederoside (48) from the host plant, Paederia scandens (Rubiaceae). This secretion apparently protects the aphid from the ladybird beetle Harmonia axyridis (Harbome, 1989 Nishida and Fukami, 1989). 

Paederoside (144) isolated from Paederia scandens and genipin (145) and kutkoside (126) from Picrorhiza kurroa displayed significant antitumor-promoting... 

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