PACT trial

Thompson PL, Meredith I, AmerenaJ, Campbell TJ, Sloman JG, Harris PJ. Effect of pravastatin compared with placebo initiated within 24 hours of onset of acute myocardial infarction or unstable angina the Pravastatin in Acute Coronary Treatment (PACT) trial. Am Heart J 2004 I48 e2. 

Ross AM, Coyne KA, Reiner JS et al. A randomized trial comparing primary angioplasty with a strategy of short-acting fibrinolysis and immediate planned rescue angioplasty in acute myocardial infarction the PACT trial. J Am Coll Cardiol. 1999 34 1954-1962. 

The PACT trial was a reevaluation of a combined approach. It stimulated further reassessment of combination therapy with the use of registries and substudies in randomized clinical trials. These more recent studies are described in detail in a section devoted to the evolution of pharmacoinvasive therapy. 

Lindley, David. The Trials of Frances Howard Pact and Fiction in the Court of King James. London Routledge, 1993. 

Common justice demands, say Sprenger and Kramer in the Malleus, that a witch should not be condemned to death unless she is convicted of her own confession. 2 According to Robbins, Once accused, the victim had to endure torture and inevitably make a confession of guilt. Every witch trial had its confessions. Similarly, every sanity hearing has its psychiatric self-incrimination the state-employed psychiatrist demonstrates to the court, from statements made by or attributed to the victim, that the patient is suffering from mental illness. The records of witch trials are as full of documented confessions of pacts with the devil and other evidences of witchcraft, as are the records of modern Institutional Psychiatry of hallucinations, delusions, and other evidences of insanity. One example of this should sufi ce here. ... 

A striking example can be seen in the results in the Plasminogen Activator Angioplasty Compatibility Trial (PACT). In this study... 

In the Plasminogen-activator Angioplasty Compatibility Trial (PACT), 606 patients with STEMI were randomized to placebo or reduced-dose recombinant tissue plasminogen activator (rt-PA) in the... 

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