P-tolylsulfonyl chloride

Materials. The tosylation method was reported previously.(Ref. 3) Y-CD was sulfonated by reaction with 6 equiv. of p-tolylsulfonyl chloride in an aqueous alkaline solution at room temperature for 1 hr. After filtering off the exess tosyl chloride, the reaction mixture was purified through a HPLC apparatus (Toyo Soda LS-410 (j) 2.5x30 cm) ... 

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