P-Barrel proteins

Lesk, A.M., Branden, C.-L, Chothia, C. Structural principles of a/p barrel proteins the packing of the interior of the sheet. Proteins 5 139-148, 1989. 

Fersht, A. and Altamirano, M. (2001) Design of novel enzymes by mutagenesis of a/p-barrel proteins. PCT Int. Appl. 83, pp. 

Values of for fatty acids bound to the soluble p-barrel protein, (3-lactoglobulin, are in the range 220-110 ns, decreasing with spin-label position down to C12 of the chain." However, it appears that the spin-label group does not enter fully into the binding pocket of p-lactoglo-bulin, which is less exposed to water than are the binding sites of serum albumin. 

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