Oxygen diffusion limited degradation examples

There is no doubt that isothermal microcalorimetry has the potential to be very useful in studies of chemical degradation. The success will be greatest for solution-state reactions for which the reacting concentration is known, but even these can be limited by physical artifacts by, for example, the slow diffusion of oxygen into the liquid from the head space. The use of this technique for solid-state reactions is certainly not impossible, but is an area where great care is needed. The technique may therefore be used readily in a preformulation environment for solution systems, but is perhaps better applied in a QC (quality control) role for well-characterized solid-state processes. 

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