Oxirane trichloromethyl

Oxirane, phenyl-. See Styrene oxide Oxirane, (trichloromethyl)-. See 1,2-Epoxy-3,3,3-trichloropropane Oxirane, trifluoro (trifluoromethyl)-. See 1,2-Epoxy-1,1,2,3,3,3-hexafluoropropane Oxirene, 2,2,2-trichloroethyl-. See Trichlorobutylene oxide Oxitol. See Ethoxyethanol Oxoacetic acid. See Glyoxalic acid 5-Oxobarbituric acid monohydrate. See Alloxan monohydrate... 

In reactions which have some analogy with the interaction of dichloro-carbene/trichloromethyl anions with ketones, 2-dichloromethyloxazolines yield chloro-oxiranes and a-chlorocarbonyl compounds (Scheme 7.18). The formation of the oxiranes is favoured with aldehydes and lower homologue ketones, whereas cyclic ketones and aryl ketones are converted preferentially into the a-chloro carbonyl derivatives [18]. 

Since the cyclopropanation is rather slow, it is postulated that the formation of dichlorooxirane goes via the addition of the trichloromethyl anion to the carbonyl group, then the cyclization of the adduct the intermediate oxirane 11 was isolated after 30-40% conversion of ketone. 

This epoxide formation takes place almost exclusively when R is an electron-attracting group e.g., 2-(trichloromethyl)oxirane is obtained from chloral and diazomethane,174 and 2-(o-nitrophenyl)oxirane from o-nitrobenzalde-hyde.175,176... 

Trichloromethyl) oxirane Trichloropropane oxide Trichloropropene oxide 1,1,1-Trichloropropene oxide 1,1,1-Trichloropropene-2,3-oxide 3,3,3-Trichloropropene oxide 1,1,1-Trichloropropylene oxide 3,3,3-Trichloropropylene oxide... 

Trichloromethyinitrile. See Trichloroacetonitrile (Trichloromethyl) oxirane. See 1,2-Epoxy-3,3,3-trichloropropane... 

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