Oxidative of allyl acetate

Furthermore, the method can be applied to the synthesis of 4-demethoxyadriamy-cinone, which is the key structure of the anti-cancer drugs, the adriamycins such as idarubicin and aimamycin (52) (Eq. 3.69). The ruthenium-catalyzed oxidation of allyl acetate SO gives the corresponding a-hydroxyketone 51 in 60% yield (Eq. 3.69) [129]. 

A 65% aldehyde selectivity for the oxidation of allyl acetate in the presence of hexamethylphosphoric triamide... 

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