Oxidative coupling method

Selective alkylation of the enamidic nitrogen in 159 with 2-iodo-4,5-methylenedioxybenzyl bromide afforded the enamino-enamide 160 (Scheme 23). Application of Heck s oxidative coupling method to 160, generated by 6-endo addition, the tetracydic enamide... 

For examples of this oxidative coupling method and leading references, see Ref. [11],... 

Phenolic or non-phenolic oxidative coupling methods have been extensively used since the 1970 s to synthesize polyoxygenated bridged biaryl compounds, as will be illustrated later in the case of steganes. Remarkably enough, the use of transition metal oxidants is particularly suited to perform intramolecular biaryl coupling whereas most other methods are better suited to intermodular coupling. 

A new synthesis of unsymmetrical tris(pyrazolyl)methane by an oxidative coupling method was proposed by Armanasco (Scheme 18).250... 

C-H/C-M Arene Arylation (Rh-Catalyzed Oxidative Coupling Methods). 259... 

C-H/C-M arene arylation methods (Rh-catalyzed oxidative coupling methods)... 

Oxidative coupling. Methods for ketone synthesis by trapping electrophilic species generated by CAN oxidation with silyl enol ethers are quite useful. 2-Tributylstannyl-l,3-dithiane and l-trimethylsiloxy-l,3-butadiene are exemplary substrates. 

Standard oxidative coupling methods for acetylenes use the Glaser method (CuCl, NH4CI, aqueous alcohol, O2) or Eglinton and Galbraith s method [Cu(OAc)a, pyridine, alcohol]. The former reaction can be accelerated by addition of JYiV A -tetramethylethylenediamine and the yield improved by using dimethoxyethane as solvent. ... 

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