2-Oxazolidones, chiral

Methoxy-1,3-bis( trimethylsilyloxy) -1,3-butadiene, 178 (1 R,2S)-N-Methylephedrine-0-pro-pionate, 308 Norephedrine, 200 Organotitanium reagents, 213 2-Oxazolidones, chiral, 225 (2R,4R)-Pentanediol, 237 Tin(II) trifluoromethanesulfonate, 301 Alkylation... 

Camphor- 10-sulfonic acid, 62 (S)-2-(l-Hydroxy-1-methylethyl)-pyrrolidine, 146 a-Methylbenzylamine, 185 Quina alkaloids, 264 Cycloaddition reactions 2-Oxazolidones, chiral, 225 Cyclopropanation Diiodomethane-Diethylzinc, 276 Simmons-Smith reagent, 275 Deprotonation Lithium amides, chiral, 159... 

Diiodomethane-Diethylzinc, 276 2-Oxazolidones, chiral, 267 8-Phenylmenthol, 243 (S)-Prolinol, 261 Simmons-Smith reagent, 275 L-Valinol, 341 Amides... 

Dimethylphenylsilane, 123 2-Oxazolidones, chiral, 225 Potassium triethylborohydride, 260 Hydroxy esters and lactones a-Hydroxy esters and lactones By hydroxylation a to the carbonyl group... 

Benzylamino)acetonitrile, 29 Chlorosulfonyl isocyanate, 80 2-Oxazolidones, chiral, 225 Palladium(II) acetate-Triphenylphos-phine, 233... 

Methyl-5-phenyl-3-(3-phenylpro-pionyl)-2-oxazolidone, 24 (S)-l-[l-Methyl-2-pyrrolidinyl]-methylpiperidine, 116, 302 Methyl p-tolyl sulfoxide, 115 Norephedrine, 200 2-Oxazolidones, chiral, 24, 225, 267 (2R,4R)-Pentanediol, 205, 237 /r[Pg.403]

Oxaziridines, 276, 277 2-Oxazolidones, chiral, 379-381 2-Oxazoline-5-ones, 151 Oxazolines, 147, 265, 588 Oxime sulfonates, 245-246 jx-Oxobis(chlorotriphenylbismuth), 381-382 Oxodiperoxymolybdenum(pyridine)(hexamethyl phosphoric triamide), 382-383 p,3-Oxohexakis( x-triinethylacetato)trimethanol-triiron(ffl), 382-383 a-Oxoketene dithioacetals, 185 Oxomethoxymolybdenum(V) 5,10,15,20-totraphcnylpoiphyrin, 383 Oxone, 442 Oxosulfenylation, 205... 

Oxazolidones, chiral, (1) and (2). Evans et al. have prepared these two chiral 2-oxazolidones by reaction of phosgene with (S)-valinol and (IS, 2R)-norephedrine, respectively, and used them as recyclable chiral auxiliaries for carboxylic acids in cnantioselective reactions of the derived imides. 

Asymmetric halogenation of carboxylic acid derivatives has also been achieved by D.A. Evans (refs. 11,12) via chiral N-acyl oxazolidones. For instance, an N-acyl oxazolidone prepared by acylation of the (4S)-benzyl-2-oxazolidone chiral auxiliary derived from (S)-phenylalanine, is converted to its (Z)-dibutyl boron enolate, which is added to a NBS slurry, at low temperature (Fig. 6) ... 

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