Oxazole palladium-catalyzed cross-coupling reactions

In contrast, if the mixture of 892 893 was transmetalated at —78°C with ZnCli and the resulting organozinc species quenched with D4-acetic acid, > 85% of the deuterium incorporation was found at C(2). The authors concluded that this organozinc species was best represented as the oxazole 895, which was subsequently used in palladium-catalyzed cross-coupling reactions (see Section 1.4.8). 

TABLE 1.71. 4-( 0-ALKENYL-2-PHENYLOXAZOLES FROM PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF 2-PHENYL-4-OXAZOLE TRIFLATE"... 

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