Overview of Eco Toxicological Concerns

ONCB is considered to be moderately toxic to humans upon acute exposure. Regardless of the route of exposure, cyanotic appearance is the predominant symptom observed in toxicity tests. Repeated exposure to sufficient concentrations of ONCB may cause methemoglobinemia [27]. This blood disorder, in which the body produces an abnormal level of methemoglobin and carmot effectively transport oxygen to the cells, may have accounted for the symptoms 

Results from OECD POV and LRTP Screening Tool 

Substance Overall Persistence (days) Characteristic Travel Distance (km) Transport Efficiency (%) 

Studies have shown moderate acute and chronic toxicity to aquatic life. A PNECa has been derived as 0.026 mg/L [27]. 

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Surface water flow may transporf microbeads until they degrade, are ingested by organisms, wash up on a shoreline, or perhaps, come to rest in sediments. Those fate and transport processes are described briefly below the potential for organisms to ingesf microbeads is discussed in Ihe overview of (eco)toxicological concerns. 

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