Other Nutrient Deficiencies in the Etiology of Pellagra

1) or vitamin Be (amd hence impadred activity of kynureninase Section 

2) may have been a significant factor in the etiology of pellagra when intaikes of tryptopham amd niacin were only manginadly adequate. 

Iron deficiency may also be a factor, because impairment of heme synthesis will both reduce the activity of the enzyme amd increase its susceptibility to proteolysis (Section 8.3.2 Oduho et ad., 1994). 

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