Other Couplings Involving Vinyltins

Paley et al. [146] have achieved the preparation of a series of enantiomerically pure 1- and 2-sulfinyldienes starting from vinyltins and halovinyl sulfoxides. Reactions involving vinyl-, 2-furanyl-, and l-methyl-3-indolyltins were used for the functionalization of -lactam rings [147]. A stereoselective construction of conjugated trienoic acids by two successive Stille couplings was reported by Thibonnet et al. [148]. 

Li et al. [149] have prepared ribonucleotide reductase inhibitors by coupling of vinyltributyltin with substituted 2-chloropyridines or the corresponding triflates. Quayle et al. [150] have carried out sequential couplings starting from 1,1-bis(tributylstannyl)-l-alkenes to afford ( )-configured vinylstannanes and hence defined trisubstituted alkenes. However, in certain cases involving bulky electrophiles, butyl migration is observed. 

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