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Oseltamivir compounds reaction

Wei and Ji have presented a new catalytic oxyphosphorylation reaction of alkenes (542) with dioxygen and dialkyl phosphite (543) leading to p-ketophosphonates (544) in good to moderate yields (Scheme 135). " New phosphonate compounds (545) have been synthesised and shown to be more potent than zanamivir against the neuraminidases of avian and human influenza viruses, including the oseltamivir-resistant strains. In comparison with zanamivir, the high afiinity of (545) could be partly... [Pg.149]


See other pages where Oseltamivir compounds reaction is mentioned: [Pg.1066]    [Pg.1177]    [Pg.255]    [Pg.961]    [Pg.231]    [Pg.180]    [Pg.402]    [Pg.161]    [Pg.872]    [Pg.402]    [Pg.400]    [Pg.208]    [Pg.433]   
See also in sourсe #XX -- [ Pg.822 ]




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Oseltamivir

Oseltamivir compounds

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