Oseltamivir Aspirin

Yang D, Pearce RE, Wang X, Gaedigk R, Wan YJ, Yan B (2009) Human carboxylesterases HCE1 and HCE2 ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. Biochem Pharmacol 77 238-247... [Pg.134]

Antacids do not affect the pharmacokinetics of oseltamivir, and there is no pharmacokinetic interaction between aspirin or paracetamol (acetaminophen) and oseltamivir. Aspirin and a variety of other drugs used for influenza management do not affect the antiviral activity of zanamivir in vitro. [Pg.810]

Aspirin. In a study, 12 healthy subjects were given a single 900-mg dose of aspirin before, during and/or after oseltamivir 75 mg twice daily for 9 doses. There was no pharmacokinetic interaction between aspirin and oseltamivir. A possible interaction was postulated since both drugs are hydrolysed by esterases and secreted by anionic tubular secretion. ... [Pg.810]

Oo C, Barrett J, Dorr A, Liu B, Ward P. Lack of phannacokinetic interaction between the cral anti-influenza M odrug oseltamivir and aspirin. Antimicrob Agents Chemo r (2002) 46, 1993-5. [Pg.810]

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