Organotin compounds, acyl

Phthalic anhydride also shows the ability to inhibit thermal destruction of polyolefins [21]. Among the organometallic compounds may be quoted organotin compounds R2Sr(OR )2, where R2 means alkyl, aryl, or cycloalkyl OR means alkoxyl, acyl, or R2Sn(CH2COORi)2, where Rj—Ci—Cm means alkyl, allyl, or benzyl Ro represents chloro-, mono-, or triorga-notin mercaptans [22,23]. 

Kosugi, M., Shimizu, Y., Migita, T. Alkylation, arylation, and vinylation of acyl chlorides by means of organotin compounds in the presence of catalytic amounts of tetrakis(triphenylphosphine)palladium °. Chem. Lett. 1977, 1423-1424. 

Ketones are also synthesized by the aluminum chloride or palladium-catalyzed acylation of organotin compounds (eq (109)) [104]. 

Also in 1977, Kosugi, Migita and coworkers reported on the use of organotin compounds for the palladium-catalyzed cross-couplings of aryl [89] and acyl hahdes [90]. The allylation of haloarenes and the arylation of acyl hahdes displayed again a remarkable wide substrate scope (Scheme 1.26) [91]. 

Various organotin reagents react with acyl and aroyl halides under mild conditions without decarbonylation to give carbonyl compounds[390,39l]. Alkyl- or alkenyltin reagents react with acyl and aroyl chlorides to give ketones[548.733,734]. One example is the preparation of the a,/3-dnsaturated 7-keto esters 860 and 861, carried out under a CO atmosphere[735]. The reaction has been applied intramolecularly to the synthesis of the macrocyclic keto... 

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