ORGANOTELLURIUM INTERMEDIATES

BIARVLS FROM SIMPLE ARENES via ORGANOTELLURIUM INTERMEDIATES 4,4-DIMETHOXY-l.I -BIPHENYL... 

This chapter is devoted mainly to the preparation of those classes of organotellurium compounds that have been more systematically investigated in past years, owing to their peculiar role as reagents or intermediate in organic synthesis, including compounds of structural, biological or theoretical interest. 

There is evidence that organotellurium compounds react with vicinal cysteine sulph-hydryl groups on squalene monooxygenase, plausibly because of the formation of unstable intermediates in which the tellurium atom is bonded to sulphhydryl groups in squalene... 

When telluroalkynes 105 are submitted to the hydrozirconation, only the vinylzirconium intermediates 106 are formed.179,181 These are captured with organotellurium halides to give bistelluroketene acetals 107 (Scheme 64).179... 

Finally, the three-center bond MO theory together with the differential orbital utilization concept prove valuable in rationalizing acceptor behavior of organotellurium trihalides (39). Direct extension of the theory to sulfur and selenium analogs is possible (though space limitations does not permit this here) and provides structural predictions for possible adducts and intermediates. 

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