ORGANIC STRUCTURES FROM SPECTRA

Previous authors have taught the principles of solving organic structures from spectra by using a combination of methods NMR, infrared spectroscopy (IR), ultraviolet spectroscopy (UV) and mass spectrometry (MS). However, the information available from UV and MS is limited in its predictive capability, and IR is useful mainly for determining the presence of functional groups, many of which are also visible in carbon-13 NMR spectra. Additional information such as elemental analysis values or molecular weights is also often presented. 

While there is no doubt in our minds that the only way to acquire expertise in obtaining "organic structures from spectra" is to practise, some students have found the following general approach to solving structural problems by a combination of spectroscopic methods helpful ... 

In the 4th Edition of Organic Structures from Spectra we have introduced problems dealing with quantitative analysis using NMR spectroscopy and problems 284 - 291 involve the analysis of mixtures of compounds. 

In this edition, we have also introduced a series of problems using two-dimensional NMR. Problems 292 - 309 represent a graded series of exercises introducing COSY, NOESY, C-H Correlation and TOCSY spectroscopy as aids to spectral analysis and as tools for identifying organic structures from spectra. 

Field, L.D., Sternell, S. and Raima, J.R. (2002) Organic Structures from Spectra (3rd edn). Wiley, New York. 

Field, L. D., Stemhell, S., Kalman, J. R., Organic Structures from Spectra, 2nd ed., John Wiley, Chichester, England, 1995. 

Wiley, 2005 and a book of problems L D. Field, S. Sternhell, and J. R. Kalman, Organic Structures from Spectra, 3rd edn, Wiley, 2003. 

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