Organic structure determination recall

As a graduate student at Manchester, Manske determined the structures of harmine and harmaline and synthesized both alkaloids. He also synthesized rutaecarpine, as he liked to recall, by accident. Another fortuitous experiment was his discovery of the use of hydrazine in the hydrolysis of phthalimides. He also collaborated at this time with A. Lapworth in one of the pioneering studies of physical organic chemistry. He was awarded the Ph.D. by Manchester in 1926. 

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